ABSTRACT
Objective: The study was undertaken to determine the proportion and pattern of Neural Tube Defects (NTD)reported at tertiary care teaching hospital in Gurugram. The incidence of NTDs were determined and comparedwith other studies done in India and other countries.Material and methods: The study was carried out in SGT Medical College Hospital and Research Institute,Gurugram. The total number of deliveries was recorded from 2017- 2019.The aborted fetuses with NTDs wereobserved in detail externally for the sex, type of NTD and other associated anomalies after obtaining ethicalclearance and written informed consent of the parents.Results: The number of deliveries conducted between 2017-2019 at SGT Medical College Hospital and ResearchInstitute, Gurugram was 2500. There were 8 babies born with NTDs (5 female and 4 male). Overall incidence ofNTDs in the present study was 3.2/1000 births with female preponderance. The incidence of fetuses withanencephaly, myelocele, meningomyelocele, craniorachischisis and encephalocele were 0.8, 1.2, 0.4, 0.4, and0.4 per 1000 births respectively.Conclusion: Birth defects like Neural Tube Defects are easily detected by routine screening tests like USG in firstand second trimester of pregnancy. Public health measures like preconception folic acid supplements andincreasing awareness about maternal care during pregnancy needs to be highlighted to decrease the incidenceof congenital anomalies and their comorbidities.
ABSTRACT
Background: The occurrence of congenital anomalies is increasing in the present era. The incidence is estimatedto be 3-7% of the congenital disorders.Aim: The present study is focused on the spina bifida and to know the incidence of spinal defects in north Indianpopulation. This study will be helpful for providing baseline data from the north Indian population.Methodology: The present study was done on 1400 fetuses which were sent by gynecology and obstetricsdepartment of GMCH Sec. 32, Chandigarh to anatomy department for autopsy purpose during period of 2008 to2017. In every case, location and morphology of spinal defects were observed.Results: The present study showed 11.7% cases with spinal defects, out of these, 1.2% spina bifida closed(occulta) and 10.5% spina bifida open defects were noted which included 1.2% ventral spinal defects, 31.7%with meningocele, 24.3% myelomeningocele, 28.6% myelocele and 12.8% with rachischisis.Conclusions: It is important to note the detection of congenital anomalies in early stage of gestation. It isadvantageous for the obstetrician in planning the line of management whether to continue the pregnancy or not.